Effect of medium or high concentrations of in-office dental bleaching gel on the human pulp response in the mandibular incisors
Douglas Augusto Roderjan, Rodrigo Stanislawczuk, Diana Gabriela Soares, Carlos Alberto de Souza Costa, Michael Willian Favoreto, Alessandra Reis, Alessandro D. Loguercio,
소속 상세정보
( Douglas Augusto Roderjan ) -
( Rodrigo Stanislawczuk ) -
( Diana Gabriela Soares ) -
( Carlos Alberto de Souza Costa ) -
( Michael Willian Favoreto ) -
( Alessandra Reis ) -
( Alessandro D. Loguercio ) -
Abstract
Objectives: The present study evaluated the pulp response of human mandibular incisors subjected to in-office dental bleaching using gels with medium or high concentrations of hydrogen peroxide (HP).
Materials and Methods: The following groups were compared: 35% HP (HP35; n = 5) or 20% HP (HP20; n = 4). In the control group (CONT; n = 2), no dental bleaching was performed. The color change (CC) was registered at baseline and after 2 days using the Vita Classical shade guide. Tooth sensitivity (TS) was also recorded for 2 days post-bleaching. The teeth were extracted 2 days after the clinical procedure and subjected to histological analysis. The CC and overall scores for histological evaluation were evaluated by the Kruskal-Wallis and Mann-Whitney tests. The percentage of patients with TS was evaluated by the Fisher exact test (α = 0.05).
Results: The CC and TS of the HP35 group were significantly higher than those of the CONT group (p < 0.05) and the HP20 group showed an intermediate response, without significant differences from either the HP35 or CONT group (p > 0.05). In both experimental groups, the coronal pulp tissue exhibited partial necrosis associated with tertiary dentin deposition. Overall, the subjacent pulp tissue exhibited a mild inflammatory response.
Conclusions: In-office bleaching therapies using bleaching gels with 20% or 35% HP caused similar pulp damage to the mandibular incisors, characterized by partial necrosis, tertiary dentin deposition, and mild inflammation.
키워드
Hydrogen peroxide; In-office bleaching; Odontoblasts
원문 및 링크아웃 정보
등재저널 정보